As the witch strives to complete a ritual, the hunter tries to track the witch down and find out its true identity. Both players access variable card decks with 50 cards each and use different resources to defeat the other side. Many tactics and strategies are possible and necessary to survive in this fight between the two powers. Embedded in the dark graphics of illustrator Maren Gutt, the fictional story of the lost colony of Roanoke comes to life.

Nine villagers are under suspicion and only the Witch knows who the real witch is. Each turn, the two players use their action pawns on active villagers to draw cards, play cards, and gain influence. Moreover, the Witch can brew powerful potions, improve their familiar, and cast enchantments and charms. Meanwhile, the Witch Hunter will be enlisting allies, claiming strategic locations, and ruthlessly investigating the villagers.

Pagan: The Fate of Roanoke has been designed as an expandable game with new cards and other content added through expansions. Each of these expansion allow you to tailor a deck to suit a particular play-style or to enable specific combinations. Expansions both large and small are planned to be available later in 2024 after the initial release at Gen Con.