Masters of Crime: Rapture is a co-operative deductive murder mystery game in which players must solve puzzles, follow clues and make decisions to solve a case. They do this using the included deck of cards, twelve hidden realistic clue documents, and the Internet. Through a choose-your-own-adventure mechanism, players make decisions that influence the course of the game and lead to solving the case in the end. One by one, they enter different realistically designed locations and encounter the various suspects. Then they choose from three different ways to deal with the situation and receive points based on their decisions. Complex puzzles and escape room elements must be solved in order to progress further in the case.

The game is closely intertwined with the real world, and players have to keep using traditional apps like Google Maps or Wikipedia to gather information. Email, detailed web pages, and cell phone calls are also part of the immersive gaming experience.