During the game, participants take turns assigning Country cards to Statement and Special Statement cards. Communication is restricted, as players can't reveal or discuss cards in their hands. However they are allowed to discuss Open cards that are on the table and can be played onto the Statements from there. And Country cards may also be played on to the Debate area to be later discussed and potentially moved to Statements. But be cautious — the number of cards played onto Debates is limited, and once exhausted, players must rely solely on their individual insights or the Open cards.

The game ends when at least two cards have been assigned to each Statement and Special Statement card. Players then flip all Statement cards to check their answers.

Featuring 126 Statements that may or may not be true, corresponding to 72 Country cards, QuizWiz provides great replay value. Players can select any of 14 setups, categorized into three different difficulty levels, adding an extra layer of variety to the game.